There are currently a couple of issues. i128 broke several non tier1-platforms with varying degrees, like NVPTX, MSP430 and powerpc.
Also, enums can’t have #[repr(u128)] yet.
I’m not sure which of those issues are needed to get fixed before stabilisation, but generally some feature always needs to ship for one full cycle in unstable or something.
Yes, please test them! The more people test a new unstable feature, the better, as then more bugs can be found.